If I got you right, you can do it via Custom commands. E.g. write MultiScript or use Internal Commands directly.
For example:
@var $path1 = 'c:\temp'
@var $path2 = 'c:\temp\22'
MC.Explorer.NewBrowser PATH="{$path1}" SIDE=LEFT
MC.Explorer.NewBrowser PATH="{$path2}" SIDE=RIGHT
Then you can bind that custom command to a button on the button panel or to a hotkey, or put it to a quicklaunch bar